Progress on the Mechanism of Action of Probiotics in Alleviating Cow's Milk Allergy

NING Miao; WU Rina; HE Kairu; BAO Yufei; ZHANG Yuxin; YANG Hui; WU Junrui

doi:10.13386/j.issn1002-0306.2024030148

Volume 46 Issue 5

Feb. 2025

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Science and Technology of Food Industry > 2025 > 46(5): 371-379. > DOI: 10.13386/j.issn1002-0306.2024030148

NING Miao, WU Rina, HE Kairu, et al. Progress on the Mechanism of Action of Probiotics in Alleviating Cow's Milk Allergy[J]. Science and Technology of Food Industry, 2025, 46(5): 371−379. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2024030148.

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Progress on the Mechanism of Action of Probiotics in Alleviating Cow's Milk Allergy

NING Miao^{1, 2,},
WU Rina^{1, 3},
HE Kairu^{1, 2},
BAO Yufei^{1, 2},
ZHANG Yuxin^{1, 3},
YANG Hui¹,
WU Junrui^{1, 2, 3, ,}

1.
Food College of Shenyang Agricultural University, Shenyang 110866, China
2.
Shenyang Key Laboratory of Microbial Fermentation Technology Innovation, Shenyang 110866, China
3.
Liaoning Food Fermentation Technology Engineering Research Center, Shenyang 110866, China

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Received Date: March 10, 2024
Available Online: December 28, 2024

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Abstract

Abstract

Cow's milk allergy is an immune-mediated response induced by the proteins found in cow's milk, which occurs early in human life and frequently affects the skin, respiratory system, and digestive system. It has now become the most common food allergy problem in infants and young children. If cow's milk allergy is not treated promptly, it will have an impact on infants' and young children's growth and development, and in severe cases, it may result in systemic anaphylactic shock or even death. Currently, probiotics have become an essential tool for treating cow's milk allergy; nevertheless, the mechanism by which probiotics regulate cow's milk allergy is somewhat complex, with no clear and precise conclusion. In this paper, the immune mechanism of cow's milk allergy, the relationship between gut microbiota and cow's milk allergy, and the mechanism of probiotics to alleviate cow's milk allergy in terms of gut flora regulation, intestinal barrier enhancement, intestinal mucosal immunity promotion, and cow's milk allergenic protein catabolism are reviewed. This study will help to explore the anti-allergic role of probiotics in gastrointestinal function and metabolism, with a view to providing new ideas for the prevention and treatment of food allergy.
- cow's milk allergy,
- probiotics,
- intestinal flora,
- intestinal barrier,
- intestinal mucosal immunity,
- mechanism of action

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References

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Science and Technology of Food Industry

Progress on the Mechanism of Action of Probiotics in Alleviating Cow's Milk Allergy

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