Science and Technology of Food Industry

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Volume 45 Issue 11
May  2024
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LIU Pengyu, WANG Kexin, ZHOU Yuyuan, et al. Progress in Construction and Food Application of Chitosan-based Nutrient Delivery System[J]. Science and Technology of Food Industry, 2024, 45(11): 396−403. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023070173.
Citation: LIU Pengyu, WANG Kexin, ZHOU Yuyuan, et al. Progress in Construction and Food Application of Chitosan-based Nutrient Delivery System[J]. Science and Technology of Food Industry, 2024, 45(11): 396−403. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023070173.
shu

Progress in Construction and Food Application of Chitosan-based Nutrient Delivery System

  • 1.

    College of Public Health and Health Sciences, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China

  • 2.

    College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China

  • 3.

    College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China

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  • Received Date: July 19, 2023
  • Available Online: March 27, 2024
    Graphical Abstract
    • Abstract
  • Chitosan is a naturally-occurring alkaline polysaccharide with excellent biocompatibility, biodegradability, low toxicity, and easy preparation. It has been widely used in the construction of delivery systems for various nutrients and bioactive substances. The chitosan-based nutrient delivery systems are mainly constructed by cross-linking, drying, layer-by-layer self-assembly, coalescence, covalent grafting, microfluidics and biosynthesis. Chitosan can be combined with carbohydrates, proteins and liposomes to form a composite carrier that can obtain more excellent performance and broaden its application in food packaging materials, slow release of bioactive substances and probiotic embedding. In addition, this paper further analyzes the obstacles and limitations of the actual application of chitosan-based nutrient delivery systems in the food industry, to provide important references for the application of chitosan-based delivery carriers in imparting new functional properties to foods, developing new food ingredients, and nutrient fortification.
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    • References (52)
  • [1]
    CARMEN P, ANTONIO C. Chitosan:A natural biopolymer with a wide and varied range of applications[J]. Molecules,2020,25(17):3981. doi: 10.3390/molecules25173981
    [2]
    BRASSELET C, PIERRE G, DUBESSAY P, et al. Modification of chitosan for the generation of functional derivatives[J]. Applied Sciences,2019,9(7):1321−1354. doi: 10.3390/app9071321
    [3]
    WANG L, DING Y, ZHANG X, et al. Isolation of a novel calcium-binding peptide from wheat germ protein hydrolysates and the prediction for its mechanism of combination[J]. Food Chemistry,2018,239:416−426. doi: 10.1016/j.foodchem.2017.06.090
    [4]
    GISOO M, WOLTERING E J, MOZAFARI M R. Applications of chitosan-based carrier as an encapsulating agent in food industry[J]. Trends in Food Science & Technology,2022,120:88−99.
    [5]
    ZENG W, HUI H, LIU Z, et al. TPP ionically cross-linked chitosan/PLGA microspheres for the delivery of NGF for peripheral nerve system repair[J]. Carbohydrate Polymers,2021,258:117684. doi: 10.1016/j.carbpol.2021.117684
    [6]
    ZHAO L, DUAN X, CAO W, et al. Effects of different drying methods on the characterization, dissolution rate and antioxidant activity of ursolic acid-loaded chitosan nanoparticles[J]. Foods,2021,10(10):2470. doi: 10.3390/foods10102470
    [7]
    谭啸, 邱婷婷, 李若男, 等. 壳聚糖纳米粒子的制备和在食品抑菌中的研究进展[J]. 食品科学,2020,41(23):347−353. [TAN X, QIU T T, LI R N, et al. Recent progress in the preparation and application of chitosan nanoparticles as an antimicrobial in food[J]. Food Science,2020,41(23):347−353.] doi: 10.7506/spkx1002-6630-20191203-044

    TAN X, QIU T T, LI R N, et al. Recent progress in the preparation and application of chitosan nanoparticles as an antimicrobial in food[J]. Food Science, 2020, 41（23）: 347−353. doi: 10.7506/spkx1002-6630-20191203-044
    [8]
    XIN S, GUO H, XI B, et al. Preparation of vitamin E microcapsules by complex coacervation and stability evaluation[J]. Modern Food Science and Technology,2017,33(7):118−124.
    [9]
    BAKRY A M, CHANG M, XIONG S B, et al. Chitosan-glucose Maillard reaction products and their preservative effects on fresh grass carp (Ctenopharyngodon idellus) fillets during cold storage[J]. Science of Food and Agriculture,2019,99(5):2158−2164. doi: 10.1002/jsfa.9408
    [10]
    杜雨涵. 基于微流控技术的微胶囊制备及其性能研究[D]. 福州:福州大学, 2020. [DU Y H. Preparation and properties of microcapsules by microfluidics[D]. Fuzhou:Fuzhou University, 2020.]

    DU Y H. Preparation and properties of microcapsules by microfluidics[D]. Fuzhou: Fuzhou University, 2020.
    [11]
    艾浩, 王文慧, 杜开峰. 石墨烯/壳聚糖复合微球的制备及其蛋白质吸附评价[J]. 中国科技论文,2020,15(12):1352−1358, 1370. [AI H, WANG W H, DU K F. Preparation of graphene/chitosan composite microspheres (G/CS microspheres) and its protein adsorption evaluation[J]. China Sciencepaper,2020,15(12):1352−1358,1370.] doi: 10.3969/j.issn.2095-2783.2020.12.002

    AI H, WANG W H, DU K F. Preparation of graphene/chitosan composite microspheres （G/CS microspheres） and its protein adsorption evaluation[J]. China Sciencepaper, 2020, 15（12）: 1352−1358,1370. doi: 10.3969/j.issn.2095-2783.2020.12.002
    [12]
    NOURAR E, WESAMELDIN I, AMAL M, et al. An innovative green synthesis approach of chitosan nanoparticles and their inhibitory activity against phytopathogenic Botrytis cinerea on strawberry leaves[J]. Scientific Reports,2022,12(1):3515. doi: 10.1038/s41598-022-07073-y
    [13]
    郑昌亮, 孙洁, 陈梦婷, 等. 鳙鱼肽壳聚糖纳米颗粒的制备及体外性质研究[J]. 食品与发酵工业,2023,49(12):17−22. [ZHENG C L, SUN J, CHEN M T, et al. Preparation and in vitro properties of bighead carp peptide chitosan nanoparticles[J]. Food and Fermentation Industries,2023,49(12):17−22.]

    ZHENG C L, SUN J, CHEN M T, et al. Preparation and in vitro properties of bighead carp peptide chitosan nanoparticles[J]. Food and Fermentation Industries, 2023, 49（12）: 17−22.
    [14]
    邢承宇, 王璐, 陈星光, 等. 香芹酚-壳聚糖纳米颗粒的制备及抑菌活性研究[J]. 食品与发酵工业,2022,48(22):82−88. [XING C Y, WANG L, CHEN X G, et al. The characterization and antifungal activity of chitosan nanoparticle loaded with carvacrol[J]. Food and Fermentation Industries,2022,48(22):82−88.]

    XING C Y, WANG L, CHEN X G, et al. The characterization and antifungal activity of chitosan nanoparticle loaded with carvacrol[J]. Food and Fermentation Industries, 2022, 48（22）: 82−88.
    [15]
    SUNARTI T C, FEBRIAN M I, RUEIANI E, et al. Some properties of chemical cross-linking biohydrogel from starch and chitosan[J]. Biomaterials,2019,2019:6.
    [16]
    TAVARES L, ZAPATA NOREÑA C P. Encapsulation of garlic extract using complex coacervation with whey protein isolate and chitosan as wall materials followed by spray drying[J]. Food Hydrocolloids,2019,89:360−369. doi: 10.1016/j.foodhyd.2018.10.052
    [17]
    张力, 张娟, 马凌艳, 等. 自组装法制备丁香酚纳米胶囊及其性能表征[J]. 食品科学,2018,39(8):198−204. [ZHANG L, ZHANG J, MA L Y, et al. Preparation and characterization of eugenol nanocapsules by self-assembly method[J]. Food Science,2018,39(8):198−204.] doi: 10.7506/spkx1002-6630-201808031

    ZHANG L, ZHANG J, MA L Y, et al. Preparation and characterization of eugenol nanocapsules by self-assembly method[J]. Food Science, 2018, 39（8）: 198−204. doi: 10.7506/spkx1002-6630-201808031
    [18]
    BUTSTRAEN C, SALAVN F. Preparation of microcapsules by complex coacervation of gum arabic and chitosan[J]. Carbohydrate Polymers,2014,99:608−616. doi: 10.1016/j.carbpol.2013.09.006
    [19]
    ZHU B, HUI H, DAN G, et al. Two novel calcium delivery systems fabricated by casein phosphopeptides and chitosan oligosaccharides:Preparation, characterization, and bioactive studies[J]. Food Hydrocolloids,2020,102:105567−105567. doi: 10.1016/j.foodhyd.2019.105567
    [20]
    CHEBA B A. Chitosan:Properties, modifications and food nanobiotechnology[J]. Procedia Manufacturing,2020,46:652−658. doi: 10.1016/j.promfg.2020.03.093
    [21]
    NICULESCU A G, GRUMEZESCU A M. Applications of chitosan-alginate-based nanoparticles-an up-to-date review[J]. Nanomaterials,2022,12(2):186. doi: 10.3390/nano12020186
    [22]
    HAMADOU A H, ZHANG J Y, CHAO C, et al. Stability of rutin using pectin-chitosan dual coating nanoliposomes[J]. LWT-Food Science and Technology,2022,170:114084. doi: 10.1016/j.lwt.2022.114084
    [23]
    张立彦, 刘小芳, 李作为. 壳聚糖与果胶复合作用研究及显微观察[J]. 食品工业科技,2016,37(20):115−120. [ZHANG L Y, LIU X F, LI Z W. Study and microscopic observation on complexation of chitosan and pectin[J]. Science and Technology of Food Industry,2016,37(20):115−120.]

    ZHANG L Y, LIU X F, LI Z W. Study and microscopic observation on complexation of chitosan and pectin[J]. Science and Technology of Food Industry, 2016, 37（20）: 115−120.
    [24]
    邱婷婷, 谭啸, 李若男, 等. 壳聚糖-单糖美拉德反应产物的制备及其在抗菌和抗氧化中的应用研究进展[J]. 食品科学,2020,41(19):327−333. [QIU T T, TAN X, LI R N, et al. Recent advances in preparation and antimicrobial and antioxidant activity of chitosan-monosaccharides Maillard reaction products[J]. Food Science,2020,41(19):327−333.] doi: 10.7506/spkx1002-6630-20190911-138

    QIU T T, TAN X, LI R N, et al. Recent advances in preparation and antimicrobial and antioxidant activity of chitosan-monosaccharides Maillard reaction products[J]. Food Science, 2020, 41（19）: 327−333. doi: 10.7506/spkx1002-6630-20190911-138
    [25]
    TENG Z, LUO Y C, WANG Q. Carboxymethyl chitosan-soy protein complex nanoparticles for the encapsulation and controlled release of vitamin D3[J]. Food Chemistry,2013,141(1):524−532. doi: 10.1016/j.foodchem.2013.03.043
    [26]
    高博, 潘晴楣, 张志鹏, 等. 两种蛋清蛋白-壳聚糖乳液负载β-胡萝卜素的性能对比研究[J]. 食品与发酵工业,2022,48(20):210−216. [GAO B, PAN Q M, ZHANG Z P, et al. The comparative study on the performance of two kinds of egg white protein-chitosan emulsions loaded with β-carotene[J]. Food and Fermentation Industries,2022,48(20):210−216.]

    GAO B, PAN Q M, ZHANG Z P, et al. The comparative study on the performance of two kinds of egg white protein-chitosan emulsions loaded with β-carotene[J]. Food and Fermentation Industries, 2022, 48（20）: 210−216.
    [27]
    李书红, 周军君, 陈桂芸, 等. 玉米醇溶蛋白-壳聚糖纳米营养递送粒子的制备及性质[J]. 农业工程学报,2021,37(16):279−286. [LI S H, ZHOU J J, CHEN G Y, et al. Preparation and properties of zein-chitosan nano-nutrient delivery particles[J]. Transactions of the Chinese Society of Agricultural Engineering,2021,37(16):279−286.] doi: 10.11975/j.issn.1002-6819.2021.16.034

    LI S H, ZHOU J J, CHEN G Y, et al. Preparation and properties of zein-chitosan nano-nutrient delivery particles[J]. Transactions of the Chinese Society of Agricultural Engineering, 2021, 37（16）: 279−286. doi: 10.11975/j.issn.1002-6819.2021.16.034
    [28]
    WANG S, YE X Q, SUN Y, et al. Nanocomplexes derived from chitosan and whey protein isolate enhance the thermal stability and slow the release of anthocyanins in simulated digestion and prepared instant coffee[J]. Food Chemistry,2021,336:127707. doi: 10.1016/j.foodchem.2020.127707
    [29]
    孙闫小凡, 柯悦, 魏团团, 等. 壳聚糖膜表面修饰脂质体研究进展[J]. 食品与发酵工业,2023,49(20):331−338. [SUN Y S F, KE Y, WEI T T, et al. Research progress on chitosan membrane surface modified liposomes[J]. Food and Fermentation Industrys,2023,49(20):331−338.]

    SUN Y S F, KE Y, WEI T T, et al. Research progress on chitosan membrane surface modified liposomes[J]. Food and Fermentation Industrys, 2023, 49（20）: 331−338.
    [30]
    HASAN M, BEN M, MICHAUX F, et al. Chitosan-coated liposomes encapsulating curcumin:Study of lipid-polysaccharide interactions and nanovesicle behavior[J]. RSC Advances,2016,6(51):15.
    [31]
    NABEL A N, HASSAN H H, ALI A A, et al. Advancement on modification of chitosan biopolymer and its potential applications[J]. International Journal of Biological Macromolecules,2020,152:681−702. doi: 10.1016/j.ijbiomac.2020.02.196
    [32]
    MENG Q Y, ZHONG S L, GAO Y, et al. Advances in polysaccharide-based nano/microcapsules for biomedical applications:A review[J]. International Journal of Biological Macromolecules,2022,220:878−891. doi: 10.1016/j.ijbiomac.2022.08.129
    [33]
    WANG X M, SUN Y, LIU Z L, et al. Preparation and characterization of chitosan/zein film loaded with lemon essential oil:Effects on postharvest quality of mushroom (Agaricus bisporus)[J]. International Journal of Biological Macromolecules,2021,192:635−643. doi: 10.1016/j.ijbiomac.2021.10.068
    [34]
    HASSAN A H A, KORANY A M, ZEINHOM M M A, et al. Effect of chitosan-gelatin coating fortified with papaya leaves and thyme extract on quality and shelf life of chicken breast fillet and Kareish cheese during chilled storage[J]. Food Microbiology,2022,371:109667. doi: 10.1016/j.ijfoodmicro.2022.109667
    [35]
    SOROUSH A, AHMAD H, BAHRAMI S, et al. Cinnamon extract loaded electrospun chitosan/gelatin membrane with antibacterial activity[J]. International Journal of Biological Macromolecules,2021,173:580−590. doi: 10.1016/j.ijbiomac.2021.01.156
    [36]
    JELENA M B, LIDIJA P, LJILJANA D, et al. Study of vitamin E microencapsulation and controlled release from chitosan/sodium lauryl ether sulfate microcapsules[J]. Carbohydrate Polymers,2021,251:116988. doi: 10.1016/j.carbpol.2020.116988
    [37]
    YANG L, CAO X Y, GAI A R, et al. Chitosan/guar gum nanoparticles to stabilize Pickering emulsion for astaxanthin encapsulation[J]. LWT-Food Science and Technology,2022,165:113727. doi: 10.1016/j.lwt.2022.113727
    [38]
    MYEONGSU J, CHOONGJIN B, KELVIN K, et al. Enhancement of the intestinal permeability of curcumin using Pickering emulsions stabilized by starch crystals and chitosan[J]. Food Chemistry,2023,405:134889. doi: 10.1016/j.foodchem.2022.134889
    [39]
    黎文建, 彭海龙, 熊华, 等. pH响应两亲性壳聚糖衍生物纳米胶束制备、表征及对维生素D3的体外释放研究[J]. 食品工业科技,2014,35(10):125−128,133. [LI W J, PENG H L, XIONG H, et al. pH-Responsive amphiphilic chitosan derivative-based nanomicelles:Preparation, characterization and in vitro release of vitamin D3[J]. Science and Technology of Food Industry,2014,35(10):125−128,133.]

    LI W J, PENG H L, XIONG H, et al. pH-Responsive amphiphilic chitosan derivative-based nanomicelles: Preparation, characterization and in vitro release of vitamin D3[J]. Science and Technology of Food Industry, 2014, 35（10）: 125−128,133.
    [40]
    IQBAL R, LIAQAT A, JAHANGIR C M F, et al. Microencapsulation:A pragmatic approach towards delivery of probiotics in gut[J]. Journal of Microencapsulation,2021,38(6):437−458. doi: 10.1080/02652048.2021.1949062
    [41]
    邓伶俐, 刘松奇, 易顺, 等. 海藻酸钠/壳聚糖气凝胶对酸面团来源植物乳杆菌的包埋分析[J]. 中国食品学报,2021,21(8):291−297. [DENG L L, LIU S Q, YI S, et al. Analysis of the encapsulation effect of Lactobacillus plantarum from sourdough by sodium alginate/chitosan aeroge[J]. Journal of Chinese Institute of Food Science and Technology,2021,21(8):291−297.]

    DENG L L, LIU S Q, YI S, et al. Analysis of the encapsulation effect of Lactobacillus plantarum from sourdough by sodium alginate/chitosan aeroge[J]. Journal of Chinese Institute of Food Science and Technology, 2021, 21（8）: 291−297.
    [42]
    厉佳怡, 王红磊, 李娅婕, 等. 壳聚糖/透明质酸钠/益生菌水凝胶的制备、表征及胃肠道缓释作用[J/OL]. 食品科学, 1−13. [2024-04-11]. http://kns.cnki.net/kcms/detail/11.2206.TS.20230927.1126.018.html. [LI J Y, WANG H L, LI Y J, et al. Preparation, characterization and sustained-release effect of chitosan/sodium hyaluronate/probiotic hydrogels in gastrointestinal tract[J/OL]. Food Science, 1−13. [2024-04-11]. http://kns.cnki.net/kcms/detail/11.2206.TS.20230927.1126.018.html.]

    LI J Y, WANG H L, LI Y J, et al. Preparation, characterization and sustained-release effect of chitosan/sodium hyaluronate/probiotic hydrogels in gastrointestinal tract[J/OL]. Food Science, 1−13. [2024-04-11]. http://kns.cnki.net/kcms/detail/11.2206.TS.20230927.1126.018.html.
    [43]
    ZHAO M G, MA A M, HE H, et al. Desalted duck egg white peptides-chitosan oligosaccharide copolymers as calcium delivery systems:Preparation, characterization and calcium release evaluation in vitro and vivo[J]. Food Research International,2020,131:108974. doi: 10.1016/j.foodres.2019.108974
    [44]
    LI C Q, XIE W R, ZHANG X, et al. Pickering emulsion stabilized by modified pea protein-chitosan composite particles as a new fat substitute improves the quality of pork sausages[J]. Meat Science,2023,197:109086. doi: 10.1016/j.meatsci.2022.109086
    [45]
    徐天琳, 韩静, 陈凤莲, 等. 不同处理方式对壳聚糖/阿拉伯胶复合颗粒稳定的高内相乳液结构和性能的影响[J]. 食品科学,2023,44(20):35−42. [XU T L, HAN J, CHEN F L, et al. Effects of different treatment methods on the structure and properties of highly internal phase emulsion with stable chitosan/gum arabic composite particles[J]. Food Science,2023,44(20):35−42.] doi: 10.7506/spkx1002-6630-20221110-106

    XU T L, HAN J, CHEN F L, et al. Effects of different treatment methods on the structure and properties of highly internal phase emulsion with stable chitosan/gum arabic composite particles[J]. Food Science, 2023, 44（20）: 35−42. doi: 10.7506/spkx1002-6630-20221110-106
    [46]
    范丽萍, 刘志伟, 焦文娟, 等. 壳寡糖复合物的制备及其功效研究进展[J]. 食品工业科技,2022,43(9):404−415. [FAN L P, LIU Z W, JIAO W J, et al. Research progress on preparation and efficacy of chiooligosaccharide complex[J]. Science and Technology of Food Industry,2022,43(9):404−415.]

    FAN L P, LIU Z W, JIAO W J, et al. Research progress on preparation and efficacy of chiooligosaccharide complex[J]. Science and Technology of Food Industry, 2022, 43（9）: 404−415.
    [47]
    MENG Q Y, ZHONG S L, WANG J, et al. Advances in chitosan-based microcapsules and their applications[J]. Carbohydrate Polymers,2023,300:120265. doi: 10.1016/j.carbpol.2022.120265
    [48]
    CHEN L, YANG T, SONG Y J, et al. Effect of xanthan-chitosan-xanthan double layer encapsulation on survival of Bifidobacterium BB01 in simulated gastrointestinal conditions, bile salt solution and yogurt[J]. LWT-Food Science and Technology,2017,81:274−280. doi: 10.1016/j.lwt.2017.04.005
    [49]
    ANAL A K, SHRESTHA S, SADIQ M B. Biopolymeric-based emulsions and their effects during processing, digestibility and bioaccessibility of bioactive compounds in food systems[J]. Food Hydrocolloids,2019,87:691−702. doi: 10.1016/j.foodhyd.2018.09.008
    [50]
    CAO C A, ZHAO S C, CHEN J X, et al. Physical properties and stability of filled hydrogel particles based on biopolymer phase separation:Influence of the ratio of protein to polysaccharide[J]. International Journal of Biological Macromolecules,2020,142:803−810. doi: 10.1016/j.ijbiomac.2019.10.021
    [51]
    ZHANG H C, ZHANG Y W, BAO E, et al. Preparation, characterization and toxicology properties of α- and β-chitosan Maillard reaction products nanoparticles[J]. International Journal of Biological Macromolecules,2016,89:287−296. doi: 10.1016/j.ijbiomac.2016.04.079
    [52]
    MENG Q Y, ZHONG S L, HE S H, et al. Synthesis and characterization of curcumin-loaded pH/reduction dual-responsive folic acid modified carboxymethyl cellulose-based microcapsules for targeted drug delivery[J]. Journal of Industrial and Engineering Chemistry,2022,105:251−258. doi: 10.1016/j.jiec.2021.09.021
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