Research of proliferation effect for bone marrow cells and cancer cells cultured in vitro with CEJSNC
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Graphical Abstract
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Abstract
In order to understand the main components of compound e- jiao slurry nanoscale components ( English abbreviation: CEJSNC) , and the proliferative effects on the bone marrow cells and cancer cells.First, CEJSNC was obtained by simulating the digestive system. Second, with using the method of pharmacology, CEJSNC produce proliferation inhibition effect on bone marrow cells and gastric cancer, breast cancer and leukemia cell was studied.The results showed that CEJSNC had inhibition to cancer, especially breast cancer cell with significant difference ( p < 0.01) , but had significant promoting effect on bone marrow cells ( p < 0.01) ; Third, to understand the auxiliary role of CEJSNC to chemotherapy in the treatment, CEJSNC will produce what kind of impact in the tumor treatment by simulating chemotherapy with DOX was studied.The results showed that CEJSNC had no effects on cancer cells with low concentration, but have an inhibitory effect on the gastric cancer cells and had a little promoting effect on breast cancer with high concentrations, compared with the blank group, the result still had significant inhibitory effect ( p < 0.01) . leukemia cells had a significant role in promoting with low and high concentration, while bone marrow cells facilitate more significant.In conclusion, the compound e- jiao slurry ( English abbreviation: CEJS) had hematopoietic function, normal people who eat it can reduce the incidence of cancer.Different cancer patients with chemotherapy should use different dose, gastric cancer patients can eat in a high doses, breast cancer can eat in a medium and small dose, leukemia patients should be smaller doses.This can be both treatment and good prognosis.
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