Determination of nitrofurazone based on fluorescence quenching of CdS quantum dots

The study had established a simple and sensitive fluorescence method for the quantitative analysis of nitrofurazone in aquatic products.The fluorescence quenching of nitrofurazone to thioglycolic acid-capped ( TGAcapped) CdS quantum dots ( QDs) had been systematically investigated by using CdS QDs as a fluorescence probe.On the basis of that, a sensitive method for the determination of nitrofurazone was developed. The linear equation was F0/F = 17467 C ( mol /L) + 0.9918, and its linear range was 2.0 × 10- 6~1.0 × 10- 4mol /L with a correlation coefficient of 0.9984. The limit of detection was 7.12 × 10- 7mol /L. Method was applied to the determination of nitrofurazone in shrimp sample.The values of recovery test obtained by the standard addition method were in the range of 95.6% ~97.0%.