Batch fermentation kinetics of ε-Polylysine by Streptomyces Albus KD-11
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Graphical Abstract
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Abstract
The kinetic models of the batch fermentation of ε-PL by Streptomyces Albus KD-11 in a 30L-bioreactor were studied. The kinetics model was proposed by using the Logistic equation for cell growth, the Luedeking Piret equation for ε-PL production and the Luedeking-Piret-like equation for consumption of glucose as substrate. Parameters were gained with nonlinear curve fit by Origin 8.1 version. The goodness-of-fit scores R2 of models are all greater than 0.980 showed good agreement of predicted values with the experimental values.Calculated results of models were compared satisfactorily with experimental data under various initial glucose concentrations (4555g/L) , the average relative error was no more than 8%. The kinetic model had guiding process in ε-PL fermentation of Streptomyces Albus KD-11.
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