Optimization on preparation of hypoglycemic peptides from apricot ( Armeniaca sibirica) hydrolyzed by papain

The optimum preparation condition of hypoglycemic peptides from apricot ( Armeniaca sibirica) hydrolyzed by papain was determined by the single factor and the response surface analysis.The results showed that the optimum hydrolysis conditions were as follows: pH7, temperature 50℃, solvent ratio 6, the enzyme amount 3% ( w /w) .The inhibition ratio to α- glucosidase was 14.22%, and the IC50value was 0.08g /mL.The peptides prepared under the achieved condition had a decent hypoglycemic effect.