Mutation breeding of high yield intracellular polysaccharide of Agaricus blazei and the evaluation of preliminary safety

In order to improve the intracellular polysaccharide yield of Agaricus blazeimurill, chemical mutagenesis method was applied to treat Agaricus blazei strains. A high yield mutant, named ABM48 was obtained with polysaccharide content 12%, which was increased by 36% than the original strain. The acute toxicity and subacute toxicity experiments showed that this mutant was safe and non-toxic. It had broad application prospects in the edible and medicinal area.