Study on antioxidant activities of fucoxanthin pigments from Sargassum Fusiform

In order to study the antioxidant activities of fucoxanthin products extracted by supercritical carbon dioxide from Sargassum Fusiform, first, the experiments of reducing power, the clean-up rates on DPPH· and preventing effect on lipid peroxidation were performed using spectrophotometry and then the function of clean-up on ·OH, O-2·free radicals and H2O2 were studied by the method of chemiluminescence. Results indicated that fucoxanthin products of Sargassum Fusiform had doseresponse relationship with antioxidant activities, throwing a weak reducing power but strong clean-up rates on ·OH, O-2·free radicals, H2O2 and DPPH·. The IC50 for clean- up rates on ·OH was 386. 29μg/mL, superior to VC’s but below VE’s, the IC50 to DPPH· was 565. 2μg/mL, about 211. 4% of the VE’s and the IC50 to O-2· was 615. 71μg/mL, less than that of VE and VC. Preventing effect on lipid peroxidation was about 1/2 times of BHT and much more powerful than VC. Therefore, fucoxanthin products from Sargassum Fusiform had well antioxidant activities, and could be developed and used as native antioxidant hopefully.