Study on fatty acid composition and assisting for lipid lowering of wild peony seed oil from Western Hunan
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摘要: 采用气相色谱法分析湘西野生牡丹籽油的脂肪酸组成,并通过50例人体试食实验探讨其辅助降血脂作用。结果表明,湘西野生牡丹籽油主要由棕榈酸6.04%、硬脂酸1.81%、油酸25.20%、亚油酸28.65%、亚麻酸37.41%组成,不饱和脂肪酸高达91.26%;湘西野生牡丹籽油可显著降低受试者的胆固醇（TC,Serum Total Cholesterol）、甘油三酯（TG,Triacylglyceride）、低密度脂蛋白胆固醇（LDL-C,Low Density Lipoprotein Cholesterol）水平,降幅分别为13.20%、35.98%、10.72%,差异具有统计学意义（p<0.05）,总有效率分别可达70.73%、81.40%、66.67%,而对高密度脂蛋白胆固醇（HDL-C,High Density Lipoprotein Cholesterol）水平无影响,表明牡丹籽油具有较好的辅助降血脂功效。Abstract: The fatty acid composition of peony seed oil from Western Hunan was testing by GC-MS method.The assist effect for lipid lowering was testing through the 50 human feeding trials.The result indicated that the compositions of peony seed oil from Western Hunan were: palmitic acid of 6.04%, stearic acid of 1.84%, oleic acid of 25.20%, linoleic acid of 28.65% and linolenic acid of 37.41%.The total concentration of polyunsaturated fatty acid reached to 91.26%.Peony seed oil from Western Hunan could lower the TC ( serum total cholesterol) , TG ( triglyceride) , LDL-C ( low density lipoprotein cholesterol) levels of human subjects obviously and the lower range were 13.20%, 35.98%, 10.72%, respectively, with statistically significant in difference, and the total effective rates could reach to 70.73%, 81.40%, 66.67%, respectively, but no effect on HDL-C ( high density lipoprotein cholesterol) levels, which indicated the peony seed oil had better assisting for lipid lowering.
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Keywords:
- peony seed oil /
- fatty acid /
- blood fat level /
- human feeding trials
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[1] 赵宣.芍药属牡丹组 (Paeoniasect.Moutan) 种间关系及栽培牡丹的起源[D].重庆:西南大学, 2007:1-2. [2] 王钦茂, 刘超, 赵帜平, 等.丹皮多糖降血糖有效成分的筛选及其作用研究[J].中国中医基础医学杂志, 2001, 7 (5) :18-21. [3] 张旃, 李明昌.丹皮酚的药理作用及机制[J].中医药信息, 2006, 23 (2) :21-23. [4] 戚军超, 周海梅, 马锦琦, 等.牡丹籽油化学成分GC-MS分析[J].粮食与油脂, 2005 (11) :22-23. [5] 高婷婷.牡丹籽油成分分析及储藏条件研究[D].北京:北京林业大学, 2012:4-6. [6] 刘兰, 刘英惠, 杨月欣.WHO/FAO新观点:总脂肪&脂肪酸膳食推荐摄入量[J].中国卫生标准管理, 2010, 1 (3) :67-71. [7] 刘军海, 崔庆新, 程霜.牛蒡籽油理化特性及脂肪酸组成的研究[J].中国油脂, 2000, 25 (2) :51-52. [8] 中华人民共和国卫生部药政局.新药 (西药) 临床研究指导原则汇编[M].1993:47-52. [9] 王芸.牡丹籽油营养成分及功能作用的研究[D].济南:山东大学, 2012:16-17. [10] 王洋, 纪姝晶, 毛文岳, 等.GC-MS法分析葵花籽蜡和牡丹籽油的不皂化物及其中的二十八烷醇[J].河北农业大学学报, 2012, 35 (4) :104-107. [11] 翟文婷, 朱献标, 李艳丽, 等.牡丹籽油成分分析及其抗氧化活性研究[J].烟台大学学报:自然科学与工程版, 2013, 26 (2) :147-150. [12] 朱献标, 翟文婷, 董秀勋, 等.牡丹籽油化学成分及功能研究进展[J].中国油脂, 2014, 39 (1) :88-91. [13] 薛伟新, 阿衣夏.高血脂症及其防治对策[J].地方病通报, 2009, 24 (6) :72-73. [14] 梁旭燕, 张凤秋.高血脂症的危害和治疗[J].中国疗养医学, 2007, 16 (1) :19-20. [15] 杨诗杰, 苏汝好, 项岚, 等.降血脂药的应用现状及研究进展[J].医药论坛杂志, 2006, 27 (1) :90-92. [16] 刘美艳.辅助降血脂功能因子研究进展[J].肉类研究, 2010 (11) :83-86. [17] HORROBIN D F, MANKU M S.How do polyunsaturated fatty acids lower plasma cholesterol levels[J].Lipids, 1983, 18 (8) :558-562.
[18] CHAN J K, BRUCE V M, MCDONALD B E.Dietary alphalinolenic acid is as effective as oleic acid and linoleic acid in lowering blood cholesterol in normolipidemic men[J].The American Journal of Clinical Nutrition, 1991, 53 (5) :1230-1234.
[19] 董振兴, 彭代银, 宣自华, 等.牡丹籽油降血脂、降血糖作用的实验研究[J].安徽医药, 2013, 17 (8) :1286-1289. [20] 朱文学, 李欣, 刘少阳, 等.牡丹籽油的毒理学研究[J].食品科学, 2010, 31 (11) :248-251. [21] 周海梅, 马锦琦, 杨志勇, 等.牡丹籽油对大、小鼠的毒性实验[J].毒理学杂志, 2009, 23 (3) :256-257.
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