Research prospects of Phytochemicals and its health effect
-
摘要: 植物化学物质是植物性食物中除已知必需营养素以外的一类生物活性物质的总称,由于其具有较强的抗氧化活性并可预防慢性疾病而引起人们的关注。本文对植物化学物质的抗氧化作用、对慢性疾病的预防效应及研究前景等进行了综述,旨在为以后的功能食品开发提供思路。Abstract: Phytochemicals in plant foods in addition to the known essential nutrients, other than the general term for a class of biologically active substances, and a cause for concern because of its strong antioxidant activity and prevention of chronic diseases.Antioxidation of phytochemicals, the effect of chronic disease prevention and research prospects are reviewed, and aims to provide ideas for the future development of function food.
-
Keywords:
- Phytochemicals /
- antioxidation /
- chronic disease /
- preventive effect /
- research prospects
-
[1] http://max.book118.com/html/2012/0729/2552633.shtm.
[2] Liu R.H.Potential Synergy of Phytochemicals in Cancer Prevention:Mechanism of Action[J].The Journal of Nutrition, 2004, 134:3479S-3485S.
[3] Cai Y Z, Luo Q, Sun M, et al.Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer[J].Life Sciences, 2004, 74:2157-2184.
[4] Halliwell B.Free radicals, antioxidants, and human disease:curiosity, cause, or consequence?[J].Lancet, 1994, 344 (8924) :721-724.
[5] Aaron JS, Niels H H Heegaard, Curtis CH.Inflammation and cancer:interweaving microRNA, free radical, cytokine and p53pathways[J].Carcinogenesis, 2010, 31 (1) :37-49.
[6] Poulson HE, Prieme H, Loft S.Role of oxidative DNA damage in cancer initiation and promotion[J].European Journal of Cancer Prevention, 1998, 7 (1) :9-16.
[7] KNChidambara Murthy, Jinhee Kim, Amit Vikram, et al.Differential inhibition of human colon cancer cells by structurally similar flavonoids of citrus[J].Food Chemistry, 2012, 132 (1) :27-34.
[8] Mok S Y, Lee S.Identification of flavonoids and flavonoid rhamnosides from Rhododendron mucronulatum for albiflorum and their inhibitory activities against aldose reductase[J].Food Chemistry, 2013, 136 (2) :969-974.
[9] Catherine C, Monia C, Caroline S, et al.Measurement of the influence of flavonoids on DNA repair kinetics using the comet assay[J].Food Chemistry, 2012, 135 (4) :2974-2981.
[10] Tang FY.The silver bullet for cancer prevention:chemopreventive effects of carotenoids[J].Biomedicine, 2012, 2 (3) :117-121.
[11] Laurencon L, Sarrazin E, Chevalier M, et al.Triterpenoid saponins from the aerial parts of Solidago virgaurea alpestris with inhibiting activity of Candida albicans yeast-hyphal conversion[J].Phytochemistry, 2013, 86:103-111.
[12] Waheed A, Barker J, Barton SJ, et al.A novel steroidal saponin glycoside from Fagonia indica induces cell-selective apoptosis or necrosis in cancer cells[J].European Journal of Pharmaceutical Sciences, 2012, 47 (2) :464-473.
[13] Pawlik A, Szczepanski MA, Klimaszewska A, et al.Phenethyl isothiocyanate-induced cytoskeletal changes and cell death in lung cancer cells[J].Food and Chemical Toxicology, 2012, 50 (10) :3577-3594.
[14] Moon PD, Kim HM.Anti-inflammatory effect of phenethyl isothiocyanate, an active ingredient of Raphanus sativus Linne[J].Food Chemistry, 2012, 131 (4) :1332-1339.
[15] Chu Y F, Liu R H.Cranberries inhibit LDL oxidation and induce LDL receptor expression in hepatocytes[J].Life Sciences, 2005, 77 (15) :1892-1901.
[16] Yang J, Martinson T E, Liu R H.Phytochemical profiles and antioxidant activities of wine grapes[J].Food Chemistry, 2009, 116 (1) :332-339.
[17] Yang J, Liu R H, Halim L.Antioxidant and antiproliferative activities of common edible nut seeds[J].LWT-Food Science and Technology, 2009, 42 (1) :1-8.
[18] Reichl S, Muller M.Effects of Flavonols on the Generation of Superoxide Anion Radicals by Xanthine Oxidaseand Stimulated Neutrophils[J].Archives of biochemistry and biophysics, 2001, 395 (1) :49-56.
[19] Yokozawa T, Kim YA, Kim HY, et al.Protective effect of persimmon peel polyphenol against high glucose-induced oxidative stress in LLC-PK1 cells[J].Food and Chemical Toxicology, 2007, 45 (10) :1979-1987.
[20] Miller N J, Castelluccio C, Tijbury L, et al.The antioxidant properties of theaflavins and their gallate esters-rsdical scavengers or metal chelators[J].FEBS Letters, 1996, 392 (1) :40-44.
[21] Shieh D E, Liu L T, Lin C C.Antioxidant and free radical scavenging effect of baicalein, baicalin and wogonin[J].Anticancer Research, 2000, 20 (5A) :2861-2865.
[22] Tournaire C, Croux S, Maurette MT, et al.Antioxidant activity of flavonoids:efficiency of singlet oxygen (1 delta g) quenching[J].J Photochem Photobiol B, 1993, 19 (3) :205-215.
[23] Cao Z, Li Y.Potent induction of cellular antioxidants and phase 2 enzymes by resveratrol in cardiomyocytes:protection against oxidative and electrophilic injury[J].European Journal of Pharmacology, 2004, 489 (12) :39-48.
[24] Miyagawa C, Chenwa, David O K.Protective effect of tea extract and TP against the Cytoxicity of 1, 42Nathoqunone in insolated rat Hepatocyles[J].Biosci Biotech Biochem, 1997, 61 (11) :1901-1905.
[25] 任祎, 马挺军, 牛西午, 等.燕麦麸皮提取物的抗氧化与降血脂作用研究[J].中国粮油学报, 2008, 23 (6) :103-106. [26] Sarti P, Avigliano L, Gorlach A, et al.Superoxide and nitric oxide-participation in cell communication[J].Cell Death&Differentiation, 2002, 9 (10) :1160-1162.
[27] Carl N, Ding A.SnapShot:reactive oxygen intermediates (ROI) [J].Cell, 2010, 140 (6) :951-951.e2.
[28] Peter C, Wootton-Beard, Ryan L.Improving public health?:The role of antioxidant-rich fruit and vegetable beverages[J].Food Research International, 2011, 44 (10) :3135-3148.
[29] Ma Q.Transcriptional responses to oxidative stress:pathological and toxicological implications[J].Pharmacol Ther, 2010, 125 (3) :376-393.
[30] Beckman SB, Ames BN.The free radical theory of aging matures[J].Physiological Reviews, 1998, 78 (2) :547-581.
[31] Block G, Patterson B, Subar A.Fruit, vegetables, and cancer prevention:a review of the epidemiological evidence[J].Nutrition and Cancer, 1992, 18 (1) :1-29.
[32] Sauvaget C, Nagano J, Hayashi M, et al.Vegetables and fruit intake and cancer mortality in the Hiroshima/Nagasaki Life Span Study[J].British Journal of Cancer, 2003, 88 (5) :689-694.
[33] Shin Y, Ryu JA, Liu R H, et al.Harvest maturity, storage temperature and relative humidity affect fruit quality, antioxidant contents and activity, and inhibition of cell proliferation of strawberry fruit[J].Postharvest Biology and Technology, 2008, 49 (2) :201-209.
[34] Sun J, Liu R H.Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells[J].Cancer Letters, 2006, 241 (1) :124-134.
[35] I|lhami Gülin.Antioxidant properties of resveratrol:A structure-activity insight[J].Innovative Food Science and Emerging Technologies, 2010, 11 (1) :210-218.
[36] Loo G.Redox-sensitive mechanisms of phytochemicalmediated inhibition of cancer cell proliferation (review) [J].The Journal of Nutritional Biochemistry, 2003, 14 (2) :64-73.
[37] Joshipura KJ, Hu FB, Manson JE, et al.The effect of fruit and vegetable intake on risk for coronary heart disease[J].Annals of Internal Medicine, 2001, 134 (12) :1106-1114.
[38] Thomson MJ, Puntmann V, Kaski JC.Atherosclerosis and oxidant stress:The end of the road for antioxidant vitamin treatment?[J].Cardiovascular Drugs and Therapy, 2007, 21 (3) :195-210.
[39] Boekholdt SM, Meuwese MC, Day NE, et al.Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women:the EPIC-Norfolk prospective population study[J].British Journal of Nutrition, 2006, 96 (3) :516-522.
[40] Joseph AV.Polyphenols and cardiovascular disease:effects on endothelial and platelet function[J].The American Journal of Clinical Nutrition, 2005, 81 (1) :292S-297S.
[41] Wang S, Melnyk J P, Tsao R, et al.How natural dietary antioxidants in fruits, vegetables and legumes promote vascular health[J].Food Research International, 2011, 44 (1) :14-22.
[42] Bryans JA, Judd PA, Ellis PR.The effect of consuming instant black tea on postprandial plasma glucose and insulin concentrations in healthy humans[J].Journal of the American College of Nutrition, 2007, 26 (5) :471-477.
[43] Pawel B, Joanna S, Monika S, et al.Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients[J].Nutrition Research, 2012, 32 (6) :421-427.
[44] Richarda A, Dolansky MM.Tea enhances insulin activity[J].Journal of Agricultural and Food Chemistry, 2002, 50 (24) :7182-7186.
[45] Fukino Y, Ikeda A, Maruyama K, et al.Randomized controlled trial for an effect of green tea-extract powder supplementation on glucose abnormalities[J].European Journal of Clinical Nutrition, 2008, 62 (8) :953-960.
[46] Asgard R, Rytter E, Basu S, et al.High intake of fruit and vegetables is related to low oxidative stress and inflammation in a group of patients with type 2 diabetes[J].Scandanavian Journal of Food and Nutrition, 2007, 51 (4) :149-158.
[47] Carter P, Gray LJ, Troughton J, et al.Fruit and vegetable intake and incidence of type 2 diabetes mellitus:Systematic review and metaanalysis[J].British Medical Journal, 2010, 341, c4229.
[48] Chu Y F, Chen Y, Black RM, et al.Type 2 diabetes-related bioactivities of coffee:Assessment of antioxidant activity, NF-κB inhibition, and stimulation of glucose uptake[J].Food Chemistry, 2011, 124 (3) :914-920.
[49] Catherine N K, Jasper KI, Michael WO, et al.Total phenolic content, antioxidant and antidiabetic properties of methanolic extract of raw and traditionally processed Kenyan indigenous food ingredients[J].LWT-Food Science and Technology, 2012, 45 (2) :269-276.
[50] Liu R H.Whole grain phytochemicals and health[J].Journal of Cereal Science, 2007, 46 (3) :207-219.
[51] Okarter N, Liu C S, Sorrells M E, et al.Phytochemical content and antioxidant activity of six diverse varieties of whole wheat[J].Food Chemistry, 2010, 119 (1) :249-257.
[52] Manach C, Scalbert A, Morand C, et al.Polyphenols:Food sources and bioavailability[J].American Journal of Clinical Nutrition, 2004, 79 (5) :727-747.
[53] Shin Y, Liu R H, Nock J F, et al.Temperature and relative humidity effects on quality, total ascorbic acid, phenolics and flavonoid concentrations, and antioxidant activity of strawberry[J].Postharvest Biology and Technology, 2007, 45 (3) :349-357.
[54] Wolosiak R, Worobiej E, Piecyk M, et al.Activities of amine and phenolic antioxidants and their changes in broad beans (Vicia faba) after freezing and steam cooking[J].International Journal of Food Science and Technology, 2010, 45 (1) :29-37.
计量
- 文章访问数: 262
- HTML全文浏览量: 31
- PDF下载量: 428
下载:
